Dates/Times:
This lecture will be given as a block course by a visiting Professor, Prof. Hyunwoo Kim from South Korea (Pohang University of Science and Technology "POSTECH"), who will be visiting our university in January/February 2023. https://lexontkfu.wixsite.com/hyunwookimlab
The lecture will take place on: Tuesdays 08-10 (CH12.0.18) January 10th, 17th, 24th and 31st.
Students are expected also to attend Prof. Reiser's lecture slot (Vorlesung 'Moderne Synthesemethoden') Monday 10-12 a.m. (H47), January 16th, 23rd,
and Prof. Reiser's seminar slot (Seminar zur Vorlesung 'Moderne Synthesemethoden') on: Friday 10-12 (H52), January 20th.
Credits:
The course is worth 3.0 credits (2 SWS). In order to complete the course, students must attend lectures and complete a coursework assignment.
Content: (Draft - subject to change)
Jan 10 (Tue 8-10, CH12.0.18):
- Importance of electroorganic synthesis in organic chemistry & industry.
- Cathodic reductions: Birch-type reduction, olefin functionalization, reductive cross-couplings (cross-electrophile coupling)
Jan 16 (Mon 10-12, H47):
- Basic introduction to electroorganic synthesis. Cyclic voltammetry, organic E-chem cell configuration. Calculating reaction efficiency
- Anodic oxidations 1: Kolbe reaction, Shono-type oxidation, cation-pool strategy, alcohol oxidation,
Jan 17 (Tue 8-10, CH12.0.18):
- Paired electrolysis: Parallel paired electrolysis, divergent paired electrolysis
Jan 20 (Fri 10-12, H52): Seminar with workshop to consolidate knowledge from Jan 16 lecture.
- Workshop on Anodic oxidation chemistry
Jan 23 (Mon 10-12, H47):
- Anodic oxidations 2: N-centered radicals, Arene oxidation, alkene oxidation, C-H bond oxidation
Jan 24 (Tue 8-10, CH12.0.18):
- Electrogenerated reagents; case studies
- Asymmetric organic electrosynthesis
Jan 31 (Tue 8-10, CH12.0.18):
- Electrophotocatalysis; merging electricity and light to achieve elusive transformations
Optional / Recommended:
Jan 18 (Wed 5pm->&n
bsp; H46): Research Lecture of Prof. Hyunwoo Kim&n
bsp;
'Radical-Polar Crossover Strategy in Organic Electrosynthesis'(part of OC Seminar WS22-23)
Date/Time/Location to be announced: Diversity, Equality and Inclusion Lecture of Prof. Hyunwoo Kim
'Teaching at a Women's College, Challenges and Opportunities for Female Scientists in South Korea'
Context and Importance of the Course:
Electroorganic synthesis has historically found applications in the synthesis of bulk chemicals. i) The Baizer process for the industrial synthesis of adiponitrile and ii) the synthesis of dimethoxycyclopentene - are realized by electrochemistry on megaton scaled per year to date for several decades. No chemical process comes close to the efficiency, economy, and sustainability of electrosynthesis in these cases.
Electroorganic synthesis is now receiving dramatic attention in the fine and pharmaceutical chemical industries, thanks to the standardization of small-scale batch lab equipment and increasing educational uptake. A review: https://pubs.acs.org/doi/10.1021/acs.chemrev.7b00397
Since electrons/holes are cheaper than chemical oxidants/reductants and cheaper than artificial photons of light, education and investment in electrochemistry is critical as Europe moves toward a more energy-sustainable future of chemical synthesis.
In Germany, this is recognized by three recent national funding initiatives:
i) Fonds der Chemischen Industrie ‘Etablierung neuer Lehrmethoden im Chemiestudium: Thema II: Elektrochemie'
ii) (U.S.A.)National Science Foundation+German Science Foundation (DFG) Lead Agency Activity in Electrosynthesis and Electrocatalysis
iii) German Science Foundation Special Priority Programme (SPP) 2370 “Nitroconversion”
At the University of Regens
burg, this is recognized
by the awarding of a new&n
bsp; International Doktoranden Kolleg (11 PhD positions:
'Chemical Catalysis with Photonic or Electrical Energy Input'
Don't get left behind - enrol on this course to learn about the 'electrifying' future of organic synthesis!
